The efficacy and function of spatholobus

Taste of taste: bitter, sweet, warm. Liver, kidney.
Indications: blood, blood circulation, Tongluo. For irregular menstruation, blood deficiency, chlorosis, numbness, rheumatism and pain. Function: The bark fiber can be used as raw material for artificial cotton, paper making and weaving; the vine is used for medicinal purposes, and it has the effect of qi, Fufeng and blood circulation; roots are used as medicine, which has the function of relaxing the muscles and promoting blood circulation, and also has the effect of killing insects. The vine and root contain phenolic ingredients, amino acids, sugars, and resins. Efficacy: blood circulation Shujin; nourishing and regulating menstruation. Indications: numbness of the hands and feet; limb paralysis; rheumatism and pain; women have irregularities; dysmenorrhea; amenorrhea.

Pharmacological effects of spatholobus suberectus:
1, the role of the hematopoietic system: According to He Shuma and other reports, Mihuadou vine decoction (100%) has an effect on blood supply to experimental rabbit anemia, which can increase blood cells and increase hemoglobin. Stronger than the fragrant flower buds and vines. In 1989, Zhang Shufang et al reported that chicken blood vine decoction (2g/kg) had no significant effect on the recovery of peripheral blood cells, hemoglobin and reticulocytes in rabbits with hemorrhagic anemia: the experimental users were free of 7 litters, including 5 litters per litter. There are 2 in each of the 2 nests, a total of 24 pieces. There were 13 females and 11 males weighing 1.42-2.58 kg. Four rabbits in the same litter were randomly assigned to Salvia miltiorrhiza, Angelica sinensis, Spatholobus suberectus and control group, with 5 in each group. Another 4 were only observed for their normal values. At the time of the experiment, blood was collected from the ear vein at 8:30 every morning (* after feeding), and the hemoglobin, red blood cell count, reticulocyte count, and the three indexes were constant, and then continuously measured for 3 days as the normal value of the rabbit. . From the 4th day, the V-shaped mouth cut from the tip of the rabbit's ear was bled at 8:30 in the morning. Once a day for 3 consecutive days, each bloodletting is equivalent to 1% of the daily weight, and the total amount released is equivalent to 50% of the total blood volume. After the blood was blown, the body fluid was replenished with 5% glucose solution, and the amount was 1% of the body weight. One day after the completion of bloodletting, each group was intragastrically administered with 20% salvia miltiorrhiza, angelica and spatholobus decoction, and was given at a dose of 2 g per lkg of body weight, and the other was given 10 ml of physiological saline per lkg of body weight for control. 1 time, for 10 consecutive days, 1 day to 13 days after the bloodletting and l6, 18, 21 days, blood was taken from the ear vein at 8:30 am every day to check the blood. The number of red blood cells before the bloodletting and the hemoglobin value was 100%. The days when the rabbits in each group recovered to 95% after bloodletting were respectively shown in Table 1 and Table 2; the normal value of reticulocytes before the bloodletting was 100%, then the blood was released. The peak time of erythrocytes and the level after 21 days are shown in Table 3. The above results indicated that spatholobus sinensis had no significant effect on the recovery of red blood cells, hemoglobin and reticulocytes in the ear vein of rabbits with hemorrhagic anemia.
2, the role of coagulation, fibrinolysis: the effect of in vitro coagulation and fibrinolysis in canine blood test dogs, after exposure to the femoral artery after anesthesia, blood collection (sow the blood in the test tube after taking blood), anticoagulant (sodium oxalate, Sodium citrate) 1 part of whole blood and 9 parts of whole blood, the plasma was separated by centrifugation, and the plasma was divided into 3 parts, and physiological saline, Danshen injection, and spatholobus injection 0.03 ml were respectively added. The time of recalcification (reflecting the internal coagulation process), prothrombin time, thrombin coagulation time, plasma fibrinogen quantification and fluoroglobulin dissolution test were measured. It can be seen that spatholobus sinensis (3mg per 1ml containing crude drug) has no significant effect on the coagulation and fibrinolysis process of isolated canine blood.
3, inhibit the heart and lower blood pressure: 50% spatholobus decoction on the in vitro and in vivo inhibition of the body. Anesthesia-free 0.43-0.5g crude drug/kg decoction and dog 0.3g crude drug/kg decoction can cause blood pressure to drop; but it has a contraction effect on the ear-free and iliac vessels.
4, anti-cancer effect: in vitro test dose of 500 ng (hot water extract) / ml, inhibition rate of JTC-26 94, 4%; phage screening anti-tumor drugs, this product has anti-phage effect.
5, the regulation of lipid metabolism: Japanese sputum with spatholobus stem decoction 6g / kg gavage for 14 days and 47 days, can increase HDL2-C, reduce HDL3-C, make HDL2-C / HDL3-C ratio Elevated, this ratio is an important indicator for evaluating lipid metabolism and arteriosclerosis.