Insulinemia is a blood-borne protozoal disease caused by Tyler's Goat, which is transmitted by hard sucking blood. It is a serious hazard.

Experts solve the disease. (1) Pathogens: Taylor is a member of the sporozoite Piriformia subfamily Piriformis wormi. The circular worm body is in the form of a ring, located at one end of the ring edge, colored in red, and the protoplasm is light blue, with a size of 0.6-1.5 microns. The punctate worm has no plasmogen and is colored in blue. It resembles a worm, but the worm body is not on the edge of red blood cells, and its diameter is slightly smaller than that of a ring. The schizontidal worms are scattered outside the red blood cells and are colored blue with a size of 0.8-1 micron.

(2) Epidemiological features: The communicator of the Insect Insect is a long-horned blood stasis. The mites are parasitic in the bushes, oak trees, and grass blades. When the sheep feed and pass by, they crawl over the body of the sheep and suck blood on the skin. Lambs are the most susceptible to the disease, especially the most common 2-6 months of age. The mortality rate is as high as 90-100%.

(3) symptoms: duration of 1-7 days, up to 10 days. At the beginning of the disease, the sheep could not keep up with the group, and the spirit was depressed, hi lying, and loss of appetite. The body is getting thinner and his performance is weak. The visible mucous membrane became pale and full of blood. The body temperature gradually increased to 41-42°C, showing high fever. Reduce or stop ruminating, drain or thin stools. Accurate alveolar sound, flow sticky or dilute watery nasal fluid. Some of the diseased sheep were excited and showed circling movements. As the course of the disease prolonged, the diseased sheep became thinner and thinner, and the body temperature dropped below room temperature. Before death, it continued to squeak and squeak, and it began to roll. Some diseased sheep have high abdominal circumference.

(4) necropsy: The body was thin, blood was thin, and the subcutaneous tissue was pale and yellowish. The heart has a large amount of small grains of bleeding. The hepatomegaly, lobular hepatic lobule, was betel-like. The gallbladder is swollen and filled with dark green bile. The greater omentum and foregut mesentery are bile dyed yellow. The kidneys are swollen and there is a large point of bleeding on the surface. Lymph node enlargement, especially in the mesenteric lymph nodes, is seen in the amount of dark gray liquid. In some cases, true gastric mucosal ulcers can be seen.

(5) Diagnosis: The onset season was the season of maniac activity; the clinical manifestations of the diseased sheep were anemia, weight loss, fever retention, conjunctival yellow stain; pathological examination of gallbladder enlargement, bile infiltration, lymphadenopathy, black-gray liquid on the cut surface; Smear seen in the presence of A. melanoides; clinical treatment with Bernier see special effects, can be diagnosed as M. cereus.

Expert treatment. 1 Prevention: a. The key to prevention of the disease lies in the elimination of fleas. In the warm season, use 0.33% of dichlorvos or 0.2-0.5% solution of trichlorfon to spray the walls of the pens to eliminate overwintering calves. b. In the endemic region of this disease, immazide phenyl urea or benier (blood insect net) is used for the injection of the sheep before the onset of the annual onset season. Bernier is assigned 7% of the 3 mg per kilogram of body weight. The solution, deep intramuscular injection, once every 20 days, is effective for the prevention of goat typhus disease. c. Preventing foreign sheep from bringing quails into the area and local sheep bringing quails into other areas. Pay attention to the quarantine work of buying and retrieving sheep.

2 treatment: a, Bernier (blood net insects): 7 mg per kilogram body weight, dubbed distilled water 7% solution for deep intramuscular injection points, once a day, once every 3 days for a course of treatment; b, Imidazole urea: 5-10% aqueous solution per kilogram of body weight, subcutaneous or intramuscular injection; c, acarbrulline: 0.6-1 mg per kilogram body weight, dubbed 5% aqueous solution, subcutaneous or muscle Injection, after 48 hours and then injection; d, yellow pigment: 3-4 mg per kilogram of body weight, dubbed 0.5-1% aqueous solution, intravenous injection, injection of drugs can not leak out of blood vessels, to avoid strong within a few days after injection Sun exposure, in order to avoid burns, if necessary, repeated injections after 24-48 hours; e, primary amine quinoline phosphate: 0.75 mg per kilogram of body weight, a daily dose of 1 dose, with 3 doses, has a special effect on the disease; f, trypan blue (cone blue pigment) per kg body weight 2-4 mg, dubbed 1% aqueous solution, intravenous injection, if necessary, the first 2 days can be repeated 1 drug.

[Composition]

The main component of this preparation is human immunoglobulin, which is prepared by cold ethanol fractionation of human plasma from healthy donors. The manufacturing process contains a step to remove anticomplementary activity and a dual viral inactivation process. It contains a suitable amount of glucose or maltose as stabilizer (see table below), but does not contain any antiseptic or antibiotic. The distribution of IgG subclasses is close to the serum level of normal subjects and maintains the bioactivity of Fc fragment of IgG.

[Indications]

1. Primary agammaglobulinemia, such as X-linked hypogammaglobulinemia, common variant immunodeficiency diseases, immunoglobulin G subclass deficiency, etc.

2. Secondary immunoglobulin deficiency diseases, such as severe infection, septicemia of newborn, etc

3. Autoimmune diseases, such as primary thrombocytopenic purpura, Kawasaki disease

Intravenous Injection Of Human Immunoglobulin

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