According to NHK TV, the research team at the University of Tokyo and the Tokyo Medical and Dental University used amino acids to develop a super-microcapsule with a diameter of only about 130,000.
In addition to glucose, which is a nutrient source, the human brain is almost inaccessible to substances in the blood. How to transport drugs into the human brain has been a major problem in the treatment of diseases such as Alzheimer's disease, and glucose is used. After covering the surface of this capsule, the specific protein in the cerebral blood vessels is combined with the glucose of the capsule, so that the capsule can be delivered to the inside of the human brain.
The research team also noticed that the specific protein can actively transport glucose in the fasting state, and when the capsule is used in the experimental rats in the fasting state, the capsule is successfully delivered to the inside of the rat brain, and the effect is up to now. About 100 times. The research team believes that if the drug ingredients are placed in this capsule, it can be expected to achieve the effects that have not been achieved so far.
Yokota Ronda, a professor at Tokyo Medical and Dental University, pointed out: "This capsule can not only cure Alzheimer's disease, but also be a powerful weapon in the treatment of neurologically related difficult diseases and mental illnesses." In addition, the University of Tokyo specializes in Professor Kataoka said: "I hope to develop nanotechnology that can deliver drugs to any part of the body in the future."
Original title: Japanese researchers successfully developed super microcapsules to deliver drugs to the human brain
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